Plaque Psoriasis Treatment Options

4 Types of Treatments

There are 4 groups of medications used to treat plaque psoriasis.

TOPICAL CREAMS

TOPICAL CREAMS

Used directly on the surface of your skin

LIGHT THERAPY

LIGHT THERAPY

Your skin, or just the psoriatic plaque, is exposed to ultraviolet light

(UVB rays or Psoralen plus UVA rays [PUVA])

BIOLOGICS

BIOLOGICS

Injectable treatments that target a possible cause of your psoriasis

ORAL SYSTEMIC THERAPIES

ORAL SYSTEMIC THERAPIES

Pills that work either throughout the body or on a specific target

“We did creams and light therapy. I wasn’t satisfied with my results.”
—Shannon

Shannon’s Story

Meet Your Injectable Biologic Options

Is it time to explore another treatment option? Biologics indicated for psoriasis work inside the body to target an overactive immune system, a possible cause of plaque psoriasis. When you talk to your dermatologist about plaque psoriasis treatment options, here are some things to think about:

FIRST 52 WEEKS OF THERAPY

Plaque psoriasis treatment vs HUMIRA®, COSENTYX® & ENBREL®
Plaque psoriasis treatment vs HUMIRA®, COSENTYX® & ENBREL®
Plaque psoriasis treatment vs HUMIRA®, COSENTYX® & ENBREL®

Once every 12 weeks (after 2 starter doses at weeks 0 and 4)

STELARA® is a prescription medicine approved to treat adults 18 years and older with moderate or severe plaque psoriasis that involves large areas or many areas of their body, who may benefit from taking injections or pills (systemic therapy) or phototherapy (treatment using ultraviolet light alone or with pills).

Blocks IL-12 and IL-23 proteins involved in inflammatory immune responses

Plaque psoriasis treatment vs HUMIRA®, COSENTYX® & ENBREL®
Plaque psoriasis treatment vs HUMIRA®, COSENTYX® & ENBREL®
Plaque psoriasis treatment vs HUMIRA®, COSENTYX® & ENBREL®

Once every other week (starting 1 week after the initial dose)

HUMIRA® is a prescription medicine used to treat adults with moderate to severe chronic plaque psoriasis who are ready for systemic therapy or phototherapy, and are under the care of a doctor who will decide if other systemic therapies are less appropriate.

Blocks TNF-alpha proteins, involved in inflammatory and immune responses

Plaque psoriasis treatment vs HUMIRA®, COSENTYX® & ENBREL®
Plaque psoriasis treatment vs HUMIRA®, COSENTYX® & ENBREL®
Plaque psoriasis treatment vs HUMIRA®, COSENTYX® & ENBREL®

Once every four weeks (after 5 starter doses at weeks 0, 1, 2, 3, 4). There are two injections per dose.

COSENTYX® is a prescription medication used to treat adults 18 years and older with moderate to severe plaque psoriasis that involves large areas or many areas of the body, and who may benefit from taking injections or pills (systemic therapy) or phototherapy (treatment with ultraviolet or UV light, alone or with systemic therapy).

Blocks IL-17A proteins, involved in inflammatory and immune responses

Plaque psoriasis treatment vs HUMIRA®, COSENTYX® & ENBREL®
Plaque psoriasis treatment vs HUMIRA®, COSENTYX® & ENBREL®
Plaque psoriasis treatment vs HUMIRA®, COSENTYX® & ENBREL®

Once every week (after twice-weekly doses for the first three months)

ENBREL® is indicated for the treatment of adult patients (18 years or older) with chronic moderate to severe plaque psoriasis who are candidates for systemic therapy or phototherapy.

Blocks TNF-alpha & beta proteins involved in inflammatory and immune responses

See how the dosing for STELARA® compares to an oral systemic therapy for the treatment of plaque psoriasis during the first 52 weeks of therapy.

OTZELA®* (apremilast)

Twice daily after starter dose (dosing milligrams vary during first five days of treatment). Blocks phosphodiesterase 4 (PDE4) enzyme involved in inflammatory and immune responses.

OTEZLA® is indicated for the treatment of patients with moderate to severe plaque psoriasis who are candidates for phototherapy or systemic therapy.

While these factors are important, there are additional considerations for selecting treatment. Please talk to your doctor about treatment options and what might be right for you.

This presentation is not intended to compare the safety and effectiveness of these treatments. Please refer to each product’s full Prescribing Information for recommended dosing and administration.

STELARA® is a 45 mg or 90 mg injection given under the skin as directed by your doctor at weeks 0, 4, and every 12 weeks thereafter. It is administered by a healthcare provider or self-injected only after proper training. If your doctor decides that you or a caregiver may give your injections at home, you should receive training on the right way to prepare and inject STELARA®. Do not try to inject yourself until you or your caregiver has been properly trained by a healthcare provider.

*Indicated trademarks are registered trademarks of their respective owners.
‡In medical studies, twice-weekly dosing for ENBREL® was also shown to be effective in the first 12 weeks.
^Based on the recommended 300-mg dose. 150 mg may be acceptable for some patients